CAS 987-24-6 Pharmaceuticals Raw Materials Betamethasone Acetate For Skin Nature

CAS 987-24-6 White Powde Betamethasone Acetate for Skin Nature From Factory

Quick details:

Product name: BetamethasoneCAS No.: 378-44-9Assay: 99%Molecular Formula: C22H29FO5Molecular Weight: 392.461Appearance: White or almost white crystalerSpecification: USP/BPMin. Order quantity: 10g

Description:

Betamethasone, dexamethasone of isomers, the role and purpose with dexamethasone acetate, the sodium and water retention effect and dose than the latter is small. Glucose metabolism and anti-inflammatory effect than hydrocortisone strong as hydrocortisone 15 times, but the effect of sodium retention hydrocortisone hundred times more, in primary adrenal hypofunction in with glucocorticoid replacement therapy used together. Also suitable for low renin and low aldosterone syndrome, autonomic neuropathy induced orthostatic hypotension. Because of the goods taken orally is prone to cause edema, more topically applying topical treatment for seborrheic eczema, dermatitis, anal, genital itching embolism. Mainly used for allergic and autoimmune inflammatory diseases. It is used for activities rheumatism, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, but also for the comprehensive treatment of certain infections.

Applications:

Corticosteroid is any of the synthetic or naturally occurring 21-carbon structure substances with four fused rings and vary functional branches attached to the ring system. Cholesterol and hormones have this carbon skeleton. The term refers to these three groups that contain a hydrogenated cyclopentano perhydro nanthrene ring system. In restricted context for medical usage by non-endocrinologists, it refers to corticosteroids. Natural corticosteroids are elaborated by the adrenal cortex in response to siological carbohydrate metabolism. According to their predominant biologic activity, they are divided into two major groups: glucocorticoid and mineralocorticoid. Glucocorticoid's chief function is to regulate carbohydrate, lipid, and protein metabolism and inhibit the release of ACTH (adrenocorticotropic hormone). Glucocorticoids also affect muscle tone and the microcirculation, participate in the maintenance of arterial blood pressure, increase gastric secretion, alter connective tissue response to injury, impede cartilage production, inhibit inflammatory, allergic, and immunologic responses, invoke shrinkage of lymtic tissue, reduce the of circulating lymcytes, and affect the functions of the central nervous system. In humans, the most important ones are cortisol, cortisone, and corticosterone. Mineralocorticoids, uniuqely aldosterone in human, regulate the balance of water and promote retention of sodium, loss of potassium. Aldosterone plays a role also in promoting tissue repair. Spironolactone is the aldosterone antagonist called potassium-sparing diuretic used in the treatment of hypertension. Corticosteroids are used in clinically for hormonal replacement therapy, for suppression of ACTH, as antineoplastic, antiallergic, and anti-inflammatory agents, and to suppress immune responses.