Basic InformationCommon Name: EstradiolCAS 50-28-2 Molecular Weight: 272.382Density: 1.2±0.1 g/cm3 Boiling Point: 445.9±45.0 °C at 760 mmHgMolecular Formula: C18H24O2 Melting Point: 173ºCFlash Point: 209.6±23.3 °C
Description
The ste salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of lar proliferation. The JAK-STAT (r and activator of transcription) pathway plays a key role in the y cytokines and growth factors and is involved in lar proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.
Application1.Estradiol valerate is the valerate of natural estradiol, which has the rmacological effect of estrogen, can promote and regulate the normal development of female genital canal and side sexual characteristics, and participate in the regulation of the function of the ovarian axis.2.For amenorrhea, menopausal syndrome, reduce milk secretion, prostate cancer, etc