Bo is considered to be the most favored cosmetic treatment among those who has a strong desire to get a rejuvenated face and reduced wrinkles and frown e is derived from Clostridium botulinum bacteria, which in large amounts can cause muscle paralysis. However, when Boed into a muscle in small concentration, it is supposed to block all ted from the nerve. As a result, the facial muscles are prevented from normal contraction and become less stiff. What is more, this great difference in treatment of uncontrolled blinking, strabismus, wrinkles and facial creases. Note that the effect is temporary and the procedure must be performed again after 3-6 months.