Naturally, urea is found in mammals, produced after decomposition of protein molecules. Synthetically, it was first produced in a laboratory by a French chemist, Hilaire Marin Rouelle, in 1773, while its industrial manufacturing started after Friedrich Wohler produced the chemical using Ammonium Cyanate.Major uses of urea include making fertilizers, adhesives, resins and polymers, and its total global production stands at 220 million tons/ year.