What is Product D4902, Dexamethasone, soluble in?
Dexamethasone is practically insoluble in water. It is soluble in ethanol, methanol, acetone, dioxane and slightly soluble in chloroform.
How should I reconstitute Product D4902, Dexamethasone, for tissue culture use?
The tissue culture grade product isdissolved in ethanol at a concentration of 1 mg/ml forming a clear, colorless solution. It is also possible to prepare a stock solution of dexamethasone in DMSO at 1.5 mM.
Do you have references for the use of Product D4902, Dexamethasone?
References can be found on the product detail page:Migliorati, G., et al., Dexamethasone and interleukins modulate apoptosis of murine thymocytes and periral T-lymcytes. rmacol Res., 30(1), 43-52 (1994).Bansal, N., et al., Apoptosis: mode of death induced in T leukemia dexamethasone and other agents. FASEB J. 5(2), 211-6 (1991).Shiao, R.T., et al., Dexamethasone and suramin inhibit proliferation and interleukin-6-mediated immunoglobulin secretion in human lymid and multiple myeloma uk. Lymma, 17(5-6)).Migliorati, G., et al, Dexamethasone induces apoptosis in mouse natural killer and cytoocytes. Immunology, 81(1), 21-26 (1994).
How long is Product D4902, Dexamethasone, stable in solution?
Dexamethasone solutions are stable for at least 30 days when stored at 4 °C and protected from light. The solution may be aliquoted and stored at -20 °C. However, insufficient information is available to assess the shelf-life of the frozen solution.
What Product D4902, Dexamethasone, been tested on?
The which this product is tested can vary from lot to lot. Some typically used 3T3 fibroblasts, BHK, L929 and CHO.
