Color | White or pale-white crystalline powder |
Usage: | Following reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C |
Physical State: | Solid |
Derived From: | Synthetic |
Solubility: | Soluble in water (0.1 mg/ml), ethanol (8 mg/ml), benzene, chloroform, methanol, DMSO (50 mM), toluene, and dilute aqueous acid, and very slightly soluble in petroleum ether. |
Storage: | Store at 4° C |
Melting Point: | 116.5-118° C (lit.) |
Boiling Point: | 512.83° C at 760 mmHg (Predicted) |
Density: | 1.18 g/cm3 (Predicted) |
Refractive Index: | N20D 1.6 (Predicted) |
IC50: | Mitochondrial permeability transition pore: IC50 = 0.8 M; Melatonin receptor 1B: IC50 = 0.02 nM (human); Melatonin receptor 1A: IC50 = 0.02 nM (human); Rattus norvegicus: IC50 = 0.08 nM; Metallothionein-3: IC50 = 64.6 nM (human); Melatonin receptor 1A: EC5050 = 0.026 nM (human); Melanophores : EC5050 = 0.063 nM (Xenopus laevis); Melatonin receptor 1B: EC5050 = 0.42 nM |
Ki Data : | Melatonin receptor 1A: Ki= 0.08 nM (human); Melatonin receptor 1B: Ki= 0.08 nM (human); Melatonin receptor 1C: Ki= 0.18 nM (human) |