Human VDR(Vitamin D3 receptor) ELISA Kit

Synonyms:Â NR1I1; Nuclear Receptor Subfamily 1 Group I Member 1; Calcitriol Receptor; 1,25-dihydroxyvitamin D3 receptor

VDR(Vitamin D3 receptor)Â Basic information

The vitamin D receptor (VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. Calcitriol (the active form of vitamin D, 1,25-(OH)2vitamin D3) binds to VDR, which then forms a heterodimer with the retinoid-X receptor. The VDR heterodimer then enters the nucleus and binds to Vitamin D responsive n genomic DNA. VDR binding results in expression or transrepression of many specific gene products. VDR is also involved in microRNA-directed post transcriptional mechanisms. In humans, the vitamin D receptor is encoded by the VDR gene located on chromosome 12q13.11.

Human VDR(Vitamin D3 receptor) ELISA Kit test method

Feiyue’s Human VDR(Vitamin D3 receptor) Elisa kit is an ELISA reagent for detection of Neutrol elastase in Serum, plasma, tissue homogenates, lysates, culture supernates and other biological fluids.

This kit uses sandwich ELISA to detect the concentration of VDR(Vitamin D3 receptor) . VDR(Vitamin D3 receptor) -specific monoclonal antibody has been pre-coated in the wells of the supplied microplate. Standards samples and controls are added to interact with the immobilized antibody. A sandwich complex is formed by additional anti- VDR(Vitamin D3 receptor) antibody with HRP-Streptavidin. TMB solution is added to react with the sandwich for ming optical by microplate reader. The concentration of  VDR(Vitamin D3 receptor) in the sample can be calculated by comparing the absorbance of the sample with the standard curve.