Beta-Nicotinamide adenine dinucleotide NAD powder CAS NO: 53-84-9

Product name: Nicotinamide-adenine Dinucleotide

CAS No.: 53-84-9

MF: C21H27N7O14P2

EINECS No.: 200-184-4

Purity: 98%

Melting point °C: 225--229

Grade Standard: Medicine Grade

Usage: Animal rmaceuticals

Nicotinamide adenine dinucleotide, abbreviated NADh+, is a coenzyme found in all living . The compound is a dinucleotide, since it consists of two nucleotides joined through their ste groups. One nucleotide contains an adenine base and the other nicotinamide.

In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another. The coenzyme is, therefore, found in two forms in : NAD+ is an oxidizing agent – it accepts electrons from other molecules and becomes reduced. This reaction forms NADH, (Nicotinamide adenine dinucleotide) which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD+. However, it is also used in other lar processes, the most notable one being a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. Because of the importance of these functions, the enzymes involved in NAD+ metabolism are targets for drug discovery.

In organisms, NAD+ can be synthesized from simple building-blocks (de novo) from the amino acids trypton or aspartic acid. In an alternative fashion, more complex components of the coenzymes are taken up from food as the vitamin called niacin. Similar compounds are released by reactions that break down the structure of NAD+. These preformed components then pass through a salvage pathway that recycles them back into the active form. Some NAD+ is also converted into nicotinamide adenine dinucleotide ste (NADP+); the chemistry of this related coenzyme is similar to that of NAD+, but it has different roles in metabolism.