Product Description
| Product Name: | Myo-Inositol, cyclic 1,2:3,4:5,6-tris(P,P'-dihydrogen diste) |
| Synonyms: | Myo-Inositol, cyclic 1,2:3,4:5,6-tris(P,P'-dihydrogen diste);Myo-inositol 1,6:2,3:4,5 tripyroste;Myo-Inositol Trispyroste, sodiuM salt;Myo-inositol trispyroste;ITPP(Myo-Inositoltripyroste);Myo-inositol trispyroste (ITPP) |
| CAS: | 802590-64-3 |
| MF: | C6H18O24P6 |
| MW: | 660.035286 |
Function
ITPP is a membrane-permeant allosteric regulator of haemoglobin oxygen binding affinity; it increases the amount of oxygen released by red blood . By lowering the binding affinity of haemoglobin for oxygen ITPP significantly shifts the oxygen–haemoglobin dissociation curve.
This oxygen-releasing effect has the potential to counteract hypoxia-mediated angiogenesis and the progression of some cancers.
ITPP significantly increased the maximal exercise capacity of normal mice and mice with heart failure. Taken orally, it increased exercise capacity 35%; 60% when the compound was taken intravenously
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