XIANTAIMA Supply 99% Raw Material Factory Supply Telmisartan with cas144701-48-4 for Antihypertensive Drugs

Product Properties

Packing & Delivery

XIANTAIMA Active rmaceutical ingredient Antihypertensive Drugs Telmisartan

Package: 125ml Sample Package; 1L Standard Package;500ml,1L/Bottle; 5L,10L/Drum; 15L,20L/Carton; or according to customers' requirement.Storage: Store in cool & dry place. Keep away from strong light and heat.

Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.

Detailed Description

XIANTAIMA Active rmaceutical ingredient Antihypertensive Drugs TelmisartanTelmisartan (INN) /t?lm??s??rt?n/ is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the management of hypertension. It was discovered by Boehringer Ingelheim and launched in 1999 as Micardis. In January 2014, Actavis as generic version of Micardis got appoval from FDA.

Function

XIANTAIMA Active rmaceutical ingredient Antihypertensive Drugs TelmisartanMechanism of actionTelmisartan is an angiotensin II receptor blocker that shows high affinity for the angiotensin II receptor type 1 (AT1), with a binding affinity 3000 times greater for AT1 than AT2.In addition to blocking the RAS, telmisartan acts as a selective modulator of peroxisome proliferator-activated receptor gamma (PPAR-γ), a central regulator of insulin and glucose metabolism. It is believed that telmisartan’s dual mode of action may provide protective benefits against the vascular and renal damage caused by diabetes and cardiovascular disease (CVD).Telmisartan's activity at the peroxisome proliferator-activated receptor delta (PPAR-δ) receptor has prompted speculation around its potential as a sport doping agent as an alternative to . Telmisartan activates PPAR-δ receptors in several tissues.

Application

XIANTAIMA Active rmaceutical ingredient Antihypertensive Drugs TelmisartanThe substance is quickly but to varying degrees absorbed from the gut. The average bioavailability is about 50% (42–100%). Food intake has no clinically relevant influence on the kinetics of telmisartan. Plasma protein binding is over 99.5%, mainly to albumin and al-1-acid glycoprotein. It has the longest half-life of any ARB (24 hours) and the largest volume of distribution among ARBs (500 liters). Less than 3% of telmisatran is inactivated by glucuronidation in the liver, and over 97% is eliminated in unchanged form via bile and faeces.

Company Profile

XIANTAIMA Active rmaceutical ingredient Antihypertensive Drugs Telmisartan

Xi’an Taima Biological Co., Ltd. was founded in 2008, is a technological export-oriented private enterprise with the Rights of Self-Managed Import and Export, specializing in active ingredients modernized and industrialization research, development, production, and sales of natural medical botany. Our factory covers an area of 6,000 square meters equipped with advanced equipment and the production process is in accordance with FDA.Since its inception, the company is aiming at providing every customer with top best quality products and superior service at a reasonable and competitive price, all the time. And in the past 9 years, we’ve gained great progress. Our products are exported to countries all over the world: USA, countries in North America, South America, European countries like UK, Germany, Sweden, Greece, Finland, Norway, France, Italy, Russia, Ukraine, Estonia, Spain, Latvia, etc. Asia countries like Malaysia, Indonesia, South Korea, Thailand, lippines, Vietnam, Singapore, etc. Our products are selling very well in these areas. And other countries like Australia, Mexico, Salvatore, Costa Rica, and so on. What’s more, for the high quality products and superior service we provide, we’ve been highly appreciated by our customers. We are getting more and more returning customer day by day. & Our Company always persist in: Top Quality Products, Exnt Professional Knowledge, Superior Service

How to Order

XIANTAIMA Active rmaceutical ingredient Antihypertensive Drugs Telmisartan

1. Make sure your quantity need and Leave us message, with your mailed details shown: Including name, address information, etc.2. We send you a PI (Proforma Invoice) for price and payment detail.3. Payment by Paypal or or T/T.4. We arrange the delivery and update you the tracking in time.

FAQ

XIANTAIMA Active rmaceutical ingredient Antihypertensive Drugs Telmisartan

Q1: Could you provide free sample for test?A1: We can provide you free sample for test, and you only need to pay the delivery cost.

Q2: Which payment terms do you accept? A2: PayPal, T/T, West Union, Bank Transfer, etc.

Q3: What's about the MOQ ?A3: It depends on different products. Usually our MOQ is 5kg.

Q4: What’s the delivery lead time?A4: We will make delivery within 1-2 days after receiving payment.

Q5: What about the delivery port? A5: Main ports in China are available (Hong Kong,Guangzhou,Shenzhen).

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