Terlipressin Acetate

Terlipressin AcetateCAS No.: 14636-12-5EINECS: 238-680-8Molecular Formula: C52H74N16O15S2Molecular Weight: 1227.37Appearance: White powderGrade: rmaceutical GradeUsage: Norepineine-resistant septic shock, bleeding esogeal varices, and for the complications of cirrhosis of the liver (esogeal and gastric variceal bleeding, ascites, liver and kidney syndrome) has important significance for the treatment of patients.

Description:

Terlipressin (trade names Teripress by New Medicon rma and Glypressin by Ferring rmaceuticals) is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepineine does not help.Indications for use include norepineine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esogeal varices.Between the patients with cirrhosis of the liver into the portal circulation of each vein and venous congestion can occur in vascular anastomosis, portal vein pressure rise nomenon. The most frequently appeared in the azygos vein anastomosis with lower esogeal varices, instant tube.Application:This product is pressurized prodrug hormone, vasopressin glycyl in into the blood after enzymatic hydrolysis in the molecule is produced a continuous low level. The portal venous pressure it generates the desired effect, but the changes of arterial blood pressure than the use of vasopressin after much smaller, and the blood of a few do not increase the fibrinolytic. Push once its role can be maintained for about 4 ~ 6h.