Hongsifang potassium sulfate compound fertilizer is developed and prepared according to the characteristics of like-chlorion and fear-chlorion crops and the content of sulfur in the cultivated soil in our country. Bisulfide compound fertilizer made of raw materials such as pure potassium sulfate and ammonium sulfate has high sulfur content, wide application range and fertilizer utilization rate and can enhance stress resistance, improve crop quality, increase yield and fertilize soil. The effect of increasing yield is remarkable, especially for like-chlorion and fear-chlorion crops.