PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as an al-Melanocyte stimulating hormone. MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating the melanocortin receptors MC1R and MC4R, but not skin tanning. Melanotan 1 and Melanotan 2 have been researched for their use in protecting against the harmful effects of ultraviolet radiation from sunlight due to their melanogenesis-stimulating properties.
 PT-141 Bremelanotide Sequence: Ac-Nle-cyclo[Asp-His-D--Arg-Trp-Lys]-OHMolecular formula: C50H68N14O10Molar Mass: 1025.2CAS 189691-06-3PubChem: CID 9941379PT-141 Structural Names: cyclo-[Nle4, Asp5, D-7, Lys10]al-MSH-(4-10)PT-141 is a metabolite of Melanotan 2