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99.5% Anti-Inflammatory Anesthetic Anodyne Procaine Hydrochloride CAS 51-05-8
Procaine Hydrochloride
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CAS:51-05-8
MF:C13H21ClN2O2
MW:272.77
EINECS:200-077-2
Synonyms:aminocaine ;anadolor ;anesthesol ;anestil ;atoxicocaine ;Benzoicacid,4-amino-,2-(diethylamino)ethylester,monohydrochloride
;benzoicacid,p-amino-,2-(diethylamino)ethylester,monohydrochloride ;bernocaine
Properties
Melting point:155-156 °C(lit.)
Boiling point:195-196°C 17mm
Flash point:195-196°C/17mm
storage temp. room temp
form Crystals or Crystalline Powder
color Colorless to white
Water Solubility soluble
Sensitive Air Sensitive
Merck 14,7757
Stability:Stable. Incompatible with strong oxidizing agents.
Safety Information
Symbol(GHS)
Description
Procaine HCl (procaine hydrochloride) is the
active ingredient in Gerovital H3 (GH3) and in the Vitacels 3 through 8. Procaine HCl is broken down rapidly by enzymes in the blood stream into PABA and DEAE. The PABA and DEAE are rapidly
conjugated and removed from the blood and excreted from the body. Because of this procaine HCl and its breakdown products (metabolites) are unable to get into the cells in any great quantity to
produce benefits. Procaine HCl will produce some benefits by itself, but they are very limited.
However when procaine HCl is complexed properly
(Koch process)(1) the procaine HCl is protected from the action of the enzymes in the blood and tissues this protection gives the procaine enough time to be transfered into the cells of the body
where it helps the cells rebuild, repair, and detoxify. This action of the procaine HCl complex is responsible for the remarkable improvements in health that result from the use of GH3 and the
Vitacel 3 - 8.
Specification
Product Name
Procaine Hydrochloride
Other Name
4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride
Assay (%)
≥99.00
Odor
Characteristic
Color
White crystalline powder
Cas No.
51-05-8
Molecular Formula
C13H20N2O2.HCl
Molecular Weight
272.77
Standard
USP34/BP2005
Function
Main functions are as follows:
1.Local anesthetic.
Applications
Main applications are as follows:
Applied in pharmaceuticalfields.
Packing
1kgor 5kg/bag, 25kg/drum
Shelf Life
24 months
Storage
Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Test Items
Specification
Test Results
Appearance
White crystals or a white crystalline powder
Conform
Identification
ABE. It appears positive reaction
Melting point
154degree~158degree
154degree~157degree
Acidity
PH 5.0~6.5
PH=5.9
Appearance of solution
Clear and colourless
Conform
Loss on drying
≤0.5%
0.07%
Heavy metals
≤0.0005%
Conform
Related substances
≤0.05%
Conform
Sulphated ash
≤0.1%
0.05%
Assay ( on dry basis )
99.0-101.0%
99.87%
Conclusion
Conform to BP2005
Application
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of
penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium
channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques