TOFACITINIB CITRATE

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Product name:TOFACITINIB CITRATE CAS:540737-29-9 Appearance:Unstable oil Assay: 99% Chemical name: (3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3-propanetricarboxylate By name: CP-690550 Description Tofacitinib, an inhibitor of Janus kinases (JAKs), is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate. It may be used as monotherapy or in combination with methotrexate or other nonbiologic disease-modifying antirheumatic drugs (DMARDs). Tofacitinib should not be used in combination with biologic DMARDs or potent immunosuppressants such as azathioprine and cyclosporine.