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Cortagen is a derivation of Cortexin with great bioregulatory function and It has gene expression patterns that alter tissue-specific patterns. Cortagen has main function on central nervous
system and secondary role in the heart and immune system.Studies have shown that Cortagen stimulates interleukin-2 expression and helps regulate immune function
primarily by reducing autoimmune responses. In animal studies, it has obvious therapeutic effect on vascular and cerebrovascular nerve regeneration after posttraumatic.Cortagen is also thought to be an aging protective peptide that may help restore DNA to a more youthful state, reduce aging, and affect gene expression that is normally
silenced by age.
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What are the benefits of Cortagen?
Cortagen (Ala-Glu-Asp-Pro) is a synthetic derivative of Cortexin. Cortexin is a well-known peptide extract used for its positive effects on memory, concentration and cerebral cortical processes.
Cortagen affects the development and maintenance of brain well-being. It has a neuroprotective effect, stimulates the regeneration process of neurons and promotes
their differentiation. At the same time, it has obvious therapeutic effect on post-traumatic blood vessel and cerebrovascular nerve regeneration. It also prevents the excessive activation of
lipid peroxidation and reduces the antioxidant activity of brain tissue.[4][5]
Here are some of the potential benefits and uses of Cortagen based on research and preclinical studies:
Cortagen for neuroprotective and Regenerative:Cortagen may have neuroprotective properties, helping to protect neurons
from damage, and support regenerative processes in neurons, potentially aiding in restoring brain function.
Cortagen for Anti-Inflammatory and Antioxidant : Cortagen might stabilize the inflammatory response in the central nervous system, promoting a balance
between pro- and anti-inflammatory pathways. It may also reduce oxidative stress and lipid peroxidation in brain tissues, thereby exerting antioxidant effects.[6][7]
Cortagen for Brain Injury and Nerve Regeneration:Animal studies suggest that Cortagen could reduce the long-term
consequences of ischemic brain injury and promote the restoration of nerve function following nerve transection or
Cortagen for Geroprotective and Anti-Aging :Cortagen has been mentioned as a geroprotective peptide, potentially
helping to restore DNA to a more youthful state, reducing senescence, and influencing gene expression often silenced by age.
What are the side effects of Cortagen?
As a peptide, Cortagan has fewer side effects than other similar drugs, and the peptide has almost no side effects at very low doses. Therefore, when using peptide therapy, you should
consult with your doctor and grasp the dosage.
Different doses of Cortagen can produce different side effects.
1)Acute use of Cortagen may produce effects similar to anxiolytics.
2)Acute and subchronic administration can result in motor stimulation without any adverse effects on the mood and affective profile of the patient.
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