Quick Details
- Usage:Chemical research
- color:white
- cas:30123-17-2
- Processing Time:1 day
- Port:Shanghai, Guangzhou,Shenzhen,
- Supply Ability: 5000 Kilograms Per Month
- Brand Name:deepiontbio
Tianeptine is an
atypical antidepressant.1 It is an agonist of the μ-opioid receptor (MOR; EC50s = 194 and 641 nM for human and mouse receptors, respectively, in a BRET assay for G protein activation) and also
has effects on the glutamate system.1,2 Tianeptine (30 mg/kg) decreases immobility in the forced swim test in wild-type, but not MOR knockout mice, indicating antidepressant-like activity
dependent on MORs.3 It increases locomotor activity at a dose of 30, but not 10 mg/kg, in the open field test and increases paw withdrawal latency in the hot-plate test in mice.
