Quick Details
- Name:Teracaine
- CAS NO.:94-24-6
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- Supply Ability: 5000 Grams Per Week
- Brand Name:Hons
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Quick detail
Tetracaine CAS:94-24-6
Tetracaine MF:C15H24N2O2
Tetracaine MW:264.36
Tetracaine EINECS:202-316-6
Tetracaine Assay:99%
Tetracaine Quality Standards:EnterpriseStandard/Pharma Grade
Tetracaine Appearance:White powder
Tetracaine Usage: Tetracaine is a topical local anesthetic for the eyes. Tetracaine works by interfering with entry of sodium ions into nerve cells. This reduces
the ability of nerves to generate an impulse and send pain sensations.
Tetracaine Description:
(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from
intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high
concentrations, tetracaine blocks release completely.
(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10
per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye,
ear, or other sensitive locations.
(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed
transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Use of Tetracaine
Tetracaine is a topical local anesthetic for the eyes; works by interfering with entry of sodium ions into nerve cells.
Synonyms
Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester
Tetracaina
Tetrakain
Anetain
EINECS 202-316-6
Pontocaine
Dicaine
Contralgin
2-(Dimethylamino)ethyl-4-(butylamino)benzolcarboxylat
Tetracainum
dicaine base
MFCD00053787
Amethocaine
2-(Dimethylamino)ethyl 4-(butylamino)benzoate
Uromucaesthin
Tetracaine