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Provide top High Quality 100% Natural Reasonable Price Mollugin CAS NO.:55481-88-4
Product Name: Mollugin
CAS NO.: 55481-88-4
MF: C17H16O4
Appearance:white powder
Detection Method: HPLC
Purity: 99%
EINECS NO.: 55481-88-4
Packing & Delivery
Mollugin
CAS NO.:55481-88-4
Package: 125ml Sample Package; 1L Standard Package;500ml,1L/Bottle; 5L,10L/Drum; 15L,20L/Carton; or according to customers'
requirement.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.
Detailed Description
Mollugin
CAS NO.:55481-88-4
Mollugin, a bioactive phytochemical isolated from Rubia cordifolia L., has shown preclinical anticancer efficacy in various cancer models.
However the effects of mollugin in regulating cancer cell survival and death remains undefined. In the present study we found that mollugin exhibited cytotoxicity on various cancer
models. The suppression of cell viability was due to the induction of mitochondria apoptosis. In addition, the presence of autophagic hallmarks was observed in mollugin-treated cells.
Notably, blockade of autophagy by a chemical inhibitor or RNA interference enhanced the cytotoxicity of mollugin. Further experiments demonstrated that phosphatidylinositide
3-kinases/protein kinase B/mammalian target of rapamycin/p70S6 kinase (PI3K/AKT/mTOR/p70S6K) and extracellular regulated protein kinases (ERK) signaling pathways participated in
mollugin-induced autophagy and apoptosis. Together, these findings support further studies of mollugin as candidate for treatment of human cancer cells.
Function
Mollugin
CAS NO.:55481-88-4
Mollugin exhibits cytotoxicity and activates autophagy in cancer models.
Mollugin induces mitochondrial apoptosis in glioblastoma cells.
Inhibition of autophagy enhances apoptosis.
Mollugin inhibits PI3K/AKT/mTOR/p70S6K signaling pathway.
Mollugin inhibits ERK signaling pathway.
Application
Mollugin
CAS NO.:55481-88-4
Mollugin Apoptosis Autophagy PI3K/AKT/mTOR/p70S6K ERK
Company Profile
Mollugin
CAS NO.:55481-88-4
Xi’an Taima Biological Co., Ltd. was founded in 2008, is a technological export-oriented private enterprise with the Rights of
Self-Managed Import and Export, specializing in active ingredients modernized and industrialization research, development, production, and sales of natural medical botany.
Our factory covers an area of 6,000 square meters equipped with advanced equipment and the production process is in accordance with FDA.
Since its inception, the company is aiming at providing every customer with top best quality products and superior service at a reasonable and competitive price, all the time.
And in the past 9 years, we’ve gained great progress.
Our products are exported to countries all over the world: USA, countries in North America, South America, European countries like UK, Germany, Sweden, Greece, Finland, Norway,
France, Italy, Russia, Ukraine, Estonia, Spain, Latvia, etc. Asia countries like Malaysia, Indonesia, South Korea, Thailand, Philippines, Vietnam, Singapore, etc. Our products are
selling very well in these areas. And other countries like Australia, Mexico, Salvatore, Costa Rica, and so on. What’s more, for the high quality products and superior service we
provide, we’ve been highly appreciated by our customers. We are getting more and more returning customer day by day.
& Our Company always persist in:
Top Quality Products, Excellent Professional Knowledge, Superior Service
How to Order
Mollugin
CAS NO.:55481-88-4
1. Make sure your quantity need and Leave us message, with your mailed details shown: Including contact name, address information,
contact phone, etc.
2. We send you a PI (Proforma Invoice) for price and payment detail.
3. Payment by Paypal or Western Union or T/T.
4. We arrange the delivery and update you the tracking number in time.
FAQ
Mollugin
CAS NO.:55481-88-4
Q1: Could you provide free sample for test?
A1: We can provide you free sample for test, and you only need to pay the delivery cost.
Q2: Which payment terms do you accept?
A2: PayPal, T/T, West Union, Bank Transfer, etc.
Q3: What's about the MOQ ?
A3: It depends on different products. Usually our MOQ is 5kg.
Q4: What’s the delivery lead time?
A4: We will make delivery within 1-2 days after receiving payment.
Q5: What about the delivery port?
A5: Main ports in China are available (Hong Kong,Guangzhou,Shenzhen).