Bivalirudin

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  Product Name Bivalirudin Acetate  Cas No. 128270-60-0 Molecular Formula C98H138N24O33 Molecular Weight 2180.33 Purity (HPLC) 99.0%min. Appearance  White powder Single Impurity (HPLC)  0.5%max Amino Acid Composition  ±10% of theoretical Peptide Content (N%) ≥80.0% Water Content (Karl Fischer)  ≤8.0% Acetate Content (HPIC) ≤12.0% MS (ESI) Consistent Mass Balance  95.0~105.0%   What is Bivalirudin Acetate? Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and blood pressure.