Fusidic acid is an antibiotic that is often used topically in creams and eyedrops but may also be given systemically as tablets or injections. The global problem of advancing antimicrobial resistance has led to a renewed interest in its use recently.
Fusidic acid is active in vitro against Stalococcus aureus, most coagulase-positive stalococci, Beta-hemolytic streptococci, Corynebacterium species, and most clostridium species. Fusidic acid has no known useful activity against enterococci or most Gram-negative bacteria (except Neisseria, Moraxella, Legionella pneumola, and Bacteroides fragilis). Fusidic acid is active in vitro and clinically against Mycobacterium leprae but has only marginal activity against Mycobacterium tuberculosis.
Fusidic Acid
Chemical Name: 16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid;(3a,4a,8a,9b,11a,13a,14b,16b,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-Nordammara-17(20),24-dien-21-oic acid
Cas No.: 6990-06-3
Molecular Formula: C31H48O6Molecular Weight: 516.71
EINECS NO.: 230-256-0
InChI: 1S/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/t18-,21?,22+,23+,24+,25-,27+,29-,30-,31-/m0/s1
Density: 1.16g/cm3
Boiling Point: 635 °CMelting Point: 190-192°CFlash Point: 198 °C
Appearance: white or almost white Crystaler
Assay:99%min
Specification:
Appearance | A white or almost white Crystaler |
Solubility | Practically insoluble in water, Freely soluble in alcohol |
Identification | IR-spectrum; TLC |
Related substances(HPLC) |
Not More Than 2.0% |
water (K.Fisher) | 1.4%-2.0% |
Sulfated ash | Not more than 0.2% |
Assay | 97.5-101.0% calculated to anhydrous substance |
Residual solvents | Methanol n.m.t 0.3% Butyl acetate n.m.t 0.1% Butanol n.m.t 0.05% |
Biological | Not less than 900U/mg, Calculated with reference to the Anhydrous substance |
water (K.Fisher) | 1.4%-2.0% |
Packaging & Shipping
Package:25kg/drum or as your request.
Storage Situation: Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Shelf Life: Two years when properly stored.
Delivery: within two weeks after receiving your prepayment.
Service we can provide:
1.Mixed container, we can mix different items in one container.
2.Quality control, before shipment, free sample for test. after shipment, keep sample for 3 years
3.Prompt shipment with professional documents
4.Packing as your request, with to before shipment.