Anti-inflammatory Glucocorticoid Drugs Betamethasone CAS 378-44-9

Anti-inflammatory Glucocorticoid Drugs Betamethasone CAS 378-44-9

Quick Details for Betamethasone

Product Name: Betamethasone

Synonyms: (11beta,16beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;16-beta-methyl-1,4-pregnadiene-9-al-fluoro-11-beta,17-al,21-triol-3,20;16-beta-Methyl-1,4-pregnadiene-9-al-fluoro-11-beta,17-al,21-triol-3,20-dione;17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-9-al-fluoro-11-bet;6beta)-;9-al-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione;9-al-fluoro-11-beta,17-al,21-trihydroxy-16-beta-methylpregna-1,4-diene;9-al-fluoro-16-beta-methyl-1,4-pregnadiene-11-beta,17-al,21-triol-3,20

CAS: 378-44-9

MF: C22H29FO5

MW: 392.46

EINECS: 206-825-4

Product Categories: Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;rmaceuticals; and Hormone;rmaceutical intermediate;CELESTONE

Melting point : 235-237°C

Storage temp.: 0-6°C

Chemical Properties : White to Off-White Solid

Usage : glucocorticoid, antiinflammatory .

Usage : Betamethasone is a glucocorticoid used as an anti-inflammatory agent.

Usage : anti-inflammatory, immunosuppressive .

Anti-inflammatory glucocorticoid drugs

Betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other rmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. , it can reduce and prevent tissue response to inflammation and eliminate heat, redness and swelling caused by local non-infectious inflammation, thereby reducing the performance of inflammation, anti-inflammatory effect of this product 0.3mg is equal to dexamethasone 0.75mg, prednisone 5mg or 25mg cortisone .

Betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension.

Currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections.

The product is contraindicated in severe psychiatric history, active duodenal ulcer, recent gastrointestinal anastomosis, heavier osteoporosis, overt diabetes, severe hypertension, virus , bacterial, fungal infections which are failed to control by the use of antimicrobial agents , thromboebitis, skin infections, such as impetigo, tinea, jock itch and so on.

Uses

Hormone drugs.It is mainly used for anti-inflammatory and anti-allergic. It is suitable for rheumatoid arthritis and various skin diseases. Betamethasone role is similiar to dexamethasone, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone and it has few side effects.